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Chapter 34 Allergic Rhinitis and Drug Allergies Sample Questions

1. A patient comes at your pharmacy to fill a prescription of clarithromycin (Biaxin) 500 mg bid for 10 days and pseudoephedrine (Sudafed) 60 mg tablet qid prn for sinus pain and congestion. Medical condition is significant for hypertension only and medication includes enalapril (Vasotec) 10 mg bid. Patient’s profile available from your pharmacy records shows that patient’s antihypertensive medication was recently filled at your store 2 weeks ago, 60 tablets dispensed. You also notice an increase in the enalapril dose due to uncontrolled BP. What should you advise the patient to take appropriate for his congestion considering his profile?
  1. A. Xylometazoline
  2. B. Diphenhydramine
  3. C. Pseudoephedrine
  4. D. Desloratadine
Answer
Ans: A
Tips: Contraindications of xylometazoline: Hypersensitivity to xylometazoline or to any ingredient in the formulation or component of the container. Angle-closure glaucoma. Concurrent therapy with MAO inhibitors. Patients with known sensitivity to adrenergic effects of drugs. Irrigation following surgical procedures in which the dura mater may have been entered, e.g., sinus and trans nasal procedures. Pseudoephedrine contraindications: Should not be used in patients with hypertension, coronary artery disease and in patients on monoamine oxidase (MAO) inhibitor therapy, or for 2 weeks after stopping MAO inhibitor drug . The concomitant use of these medications may cause a rise in high blood pressure or hypertensive crisis.
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